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Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury

BACKGROUND & AIMS: Biliary-committed progenitor cells (small cholangiocytes, SMCCs) from small bile ducts are more resistant to hepatobiliary injury than large mouse cholangiocytes (LGCCs) from large bile ducts. The definitive endoderm marker, FoxA2 is the key transcriptional factor that regulat...

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Bibliografske podrobnosti
izdano v:Hepatology
Main Authors: McDaniel, Kelly, Meng, Fanyin, Wu, Nan, Sato, Keisaku, Venter, Julie, Bernuzzi, Francesca, Invernizzi, Pietro, Zhou, Tianhao, Kyritsi, Konstantina, Wan, Ying, Huang, Qiaobing, Onori, Paolo, Francis, Heather, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258713/
https://ncbi.nlm.nih.gov/pubmed/27639079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28831
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