Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury

BACKGROUND & AIMS: Biliary-committed progenitor cells (small cholangiocytes, SMCCs) from small bile ducts are more resistant to hepatobiliary injury than large mouse cholangiocytes (LGCCs) from large bile ducts. The definitive endoderm marker, FoxA2 is the key transcriptional factor that regulat...

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Gepubliceerd in:Hepatology
Hoofdauteurs: McDaniel, Kelly, Meng, Fanyin, Wu, Nan, Sato, Keisaku, Venter, Julie, Bernuzzi, Francesca, Invernizzi, Pietro, Zhou, Tianhao, Kyritsi, Konstantina, Wan, Ying, Huang, Qiaobing, Onori, Paolo, Francis, Heather, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258713/
https://ncbi.nlm.nih.gov/pubmed/27639079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28831
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