Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury

BACKGROUND & AIMS: Biliary-committed progenitor cells (small cholangiocytes, SMCCs) from small bile ducts are more resistant to hepatobiliary injury than large mouse cholangiocytes (LGCCs) from large bile ducts. The definitive endoderm marker, FoxA2 is the key transcriptional factor that regulat...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: McDaniel, Kelly, Meng, Fanyin, Wu, Nan, Sato, Keisaku, Venter, Julie, Bernuzzi, Francesca, Invernizzi, Pietro, Zhou, Tianhao, Kyritsi, Konstantina, Wan, Ying, Huang, Qiaobing, Onori, Paolo, Francis, Heather, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258713/
https://ncbi.nlm.nih.gov/pubmed/27639079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28831
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