Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2(−/−) mice by diminishing senescence of cholangiocytes

Secretin receptor (SR), only expressed by cholangiocytes, plays a key role in the regulation of biliary damage and liver fibrosis. The aim of this study was to determine the effects of genetic depletion of SR in Mdr2(−/−) mice on intrahepatic biliary mass, liver fibrosis, senescence and angiogenesis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Zhou, Tianhao, Wu, Nan, Meng, Fanyin, Venter, Julie, Giang, Thao K, Francis, Heather, Kyritsi, Konstantina, Wu, Chaodong, Franchitto, Antonio, Alvaro, Domenico, Marzioni, Marco, Onori, Paolo, Mancinelli, Romina, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214714/
https://ncbi.nlm.nih.gov/pubmed/29977037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0093-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados