Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury

BACKGROUND & AIMS: Biliary-committed progenitor cells (small cholangiocytes, SMCCs) from small bile ducts are more resistant to hepatobiliary injury than large mouse cholangiocytes (LGCCs) from large bile ducts. The definitive endoderm marker, FoxA2 is the key transcriptional factor that regulat...

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Pubblicato in:Hepatology
Autori principali: McDaniel, Kelly, Meng, Fanyin, Wu, Nan, Sato, Keisaku, Venter, Julie, Bernuzzi, Francesca, Invernizzi, Pietro, Zhou, Tianhao, Kyritsi, Konstantina, Wan, Ying, Huang, Qiaobing, Onori, Paolo, Francis, Heather, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258713/
https://ncbi.nlm.nih.gov/pubmed/27639079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28831
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