Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury

BACKGROUND & AIMS: Biliary-committed progenitor cells (small cholangiocytes, SMCCs) from small bile ducts are more resistant to hepatobiliary injury than large mouse cholangiocytes (LGCCs) from large bile ducts. The definitive endoderm marker, FoxA2 is the key transcriptional factor that regulat...

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Publicat a:Hepatology
Autors principals: McDaniel, Kelly, Meng, Fanyin, Wu, Nan, Sato, Keisaku, Venter, Julie, Bernuzzi, Francesca, Invernizzi, Pietro, Zhou, Tianhao, Kyritsi, Konstantina, Wan, Ying, Huang, Qiaobing, Onori, Paolo, Francis, Heather, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258713/
https://ncbi.nlm.nih.gov/pubmed/27639079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28831
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