A systematic method for identifying small-molecule modulators of protein–protein interactions

Discovering small-molecule modulators of protein–protein interactions is a challenging task because of both the generally noncontiguous, large protein surfaces that form these interfaces and the shortage of high-throughput approaches capable of identifying such rare inhibitors. We describe here a ro...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Horswill, Alexander R., Savinov, Sergey N., Benkovic, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15498867/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406999101
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