Small Molecule Modulation of MEMO1 Protein-Protein Interactions

MEMO1 (mediator of ErbB2-driven cell motility) is upregulated in breast tumors and has been correlated with poor prognosis in patients. As a scaffolding protein that binds to phosphorylated-tyrosine residues on receptors such as estrogen receptor and ErbB2, MEMO1 levels can influence phosphorylation...

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Udgivet i:J Endocr Soc
Main Authors: Pollock, Julie A, Labrecque, Courtney L, Hilton, Cassidy N, Airas, Justin, Blake, Alexis, Rubenstein, Kristen J, Parish, Carol A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Tumor Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089257/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.2110
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