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Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
Human fatty acid synthase is a large homodimeric multifunctional enzyme that synthesizes palmitic acid. The unique carboxyl terminal thioesterase domain of fatty acid synthase hydrolyzes the growing fatty acid chain and plays a critical role in regulating the chain length of fatty acid released. Als...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15507492/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406901101 |
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