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Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain

Human fatty acid synthase is a large homodimeric multifunctional enzyme that synthesizes palmitic acid. The unique carboxyl terminal thioesterase domain of fatty acid synthase hydrolyzes the growing fatty acid chain and plays a critical role in regulating the chain length of fatty acid released. Als...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Chakravarty, Bornali, Gu, Ziwei, Chirala, Subrahmanyam S., Wakil, Salih J., Quiocho, Florante A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15507492/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406901101
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