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Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
Human fatty acid synthase is a large homodimeric multifunctional enzyme that synthesizes palmitic acid. The unique carboxyl terminal thioesterase domain of fatty acid synthase hydrolyzes the growing fatty acid chain and plays a critical role in regulating the chain length of fatty acid released. Als...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524853/ https://ncbi.nlm.nih.gov/pubmed/15507492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406901101 |
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