ロード中...
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer
Some cancers evade targeted therapies through a mechanism known as lineage plasticity, whereby tumor cells acquire phenotypic characteristics of a cell lineage whose survival no longer depends on the drug target. We use in vitro and in vivo human prostate cancer models to show that these tumors can...
保存先:
| 出版年: | Science |
|---|---|
| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5247742/ https://ncbi.nlm.nih.gov/pubmed/28059768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah4307 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|