ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis

Half of all prostate cancers are caused by the TMPRSS2–ERG genefusion, which enables androgens to drive expression of the normally silent E26 transformation-specific (ETS) transcription factor ERG in prostate cells(1,2). Recent genomic landscape studies of such cancers(3–8) have reported recurrent p...

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Publicado no:Nature
Main Authors: Bose, Rohit, Karthaus, Wouter R., Armenia, Joshua, Abida, Wassim, Iaquinta, Phillip J., Zhang, Zeda, Wongvipat, John, Wasmuth, Elizabeth V., Shah, Neel, Sullivan, Patrick S., Doran, Michael G., Wang, Ping, Patruno, Anna, Zhao, Yilin, Zheng, Deyou, Schultz, Nikolaus, Sawyers, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576182/
https://ncbi.nlm.nih.gov/pubmed/28614298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22820
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