The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

The HIPPO pathway is an evolutionary conserved regulator of organ size that controls both cell proliferation and death. This pathway has an important role in mediating cell death in response to oxidative stress through the inactivation of Yes-associated protein (YAP) and inhibition of anti-oxidant g...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Rajesh, Kamindla, Krishnamoorthy, Jothilatha, Gupta, Jyotsana, Kazimierczak, Urszula, Papadakis, Andreas I., Deng, Zhilin, Wang, Shuo, Kuninaka, Shinji, Koromilas, Antonis E.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239457/
https://ncbi.nlm.nih.gov/pubmed/27409837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10480
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