In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice

BACKGROUND: Mosaicism, the presence of genetically distinct cell populations within an organism, has emerged as an important contributor to disease. Mutational events occurring during embryonic development can cause mosaicism in any tissue, but the influence of environmental factors on levels of mos...

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Veröffentlicht in:Environ Health Perspect
Hauptverfasser: Meier, Matthew J., O’Brien, Jason M., Beal, Marc A., Allan, Beverly, Yauk, Carole L., Marchetti, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Institute of Environmental Health Sciences 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226697/
https://ncbi.nlm.nih.gov/pubmed/27448386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP211
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