In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice

BACKGROUND: Mosaicism, the presence of genetically distinct cell populations within an organism, has emerged as an important contributor to disease. Mutational events occurring during embryonic development can cause mosaicism in any tissue, but the influence of environmental factors on levels of mos...

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Bibliografiske detaljer
Udgivet i:Environ Health Perspect
Main Authors: Meier, Matthew J., O’Brien, Jason M., Beal, Marc A., Allan, Beverly, Yauk, Carole L., Marchetti, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226697/
https://ncbi.nlm.nih.gov/pubmed/27448386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP211
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