Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

Although many environmental agents are established male germ cell mutagens, few are known to induce mutations in spermatogonial stem cells. Stem cell mutations are of great concern because they result in a permanent increase in the number of mutations carried in sperm. We investigated mutation induc...

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Bibliografiska uppgifter
I publikationen:Toxicol Sci
Huvudupphovsmän: O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Mutagenic Effects of Benzo(a)pyrene in Mouse Sperm Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960908/
https://ncbi.nlm.nih.gov/pubmed/27208087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw088
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