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Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

Although many environmental agents are established male germ cell mutagens, few are known to induce mutations in spermatogonial stem cells. Stem cell mutations are of great concern because they result in a permanent increase in the number of mutations carried in sperm. We investigated mutation induc...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Sci
Hoofdauteurs: O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960908/
https://ncbi.nlm.nih.gov/pubmed/27208087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw088
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