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Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia

Although many environmental agents are established male germ cell mutagens, few are known to induce mutations in spermatogonial stem cells. Stem cell mutations are of great concern because they result in a permanent increase in the number of mutations carried in sperm. We investigated mutation induc...

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Библиографические подробности
Опубликовано в: :Toxicol Sci
Главные авторы: O’Brien, Jason M., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960908/
https://ncbi.nlm.nih.gov/pubmed/27208087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw088
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