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In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses that Deplete Ovarian Follicles in Mice

Polycyclic aromatic hydrocarbons (PAHs) like benzo[a]pyrene (BaP) are ubiquitous environmental contaminants formed during incomplete combustion of organic materials. Our prior work showed that transplacental exposure to BaP depletes ovarian follicles and increases prevalence of epithelial ovarian tu...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Luderer, Ulrike, Meier, Matthew J., Lawson, Gregory W., Beal, Marc A., Yauk, Carole L., Marchetti, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615722/
https://ncbi.nlm.nih.gov/pubmed/30353947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22261
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