Paternal exposure to benzo(a)pyrene induces genome-wide mutations in mouse offspring

Understanding the effects of environmental exposures on germline mutation rates has been a decades-long pursuit in genetics. We used next-generation sequencing and comparative genomic hybridization arrays to investigate genome-wide mutations in the offspring of male mice exposed to benzo(a)pyrene (B...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Beal, Marc A., Meier, Matthew J., Williams, Andrew, Rowan-Carroll, Andrea, Gagné, Rémi, Lindsay, Sarah J., Fitzgerald, Tomas, Hurles, Matthew E., Marchetti, Francesco, Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586636/
https://ncbi.nlm.nih.gov/pubmed/31240266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0476-5
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