Effects of deletion of the transcription factor Nrf2 and benzo[a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice

Polycyclic aromatic hydrocarbons, like benzo[a]pyrene (BaP), are ubiquitous environmental pollutants and potent ovarian toxicants. The transcription factor NRF2 is an important regulator of the cellular response to electrophilic toxicants like BaP and to oxidative stress. NRF2 regulates transcriptio...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Lim, Jinhwan, Ortiz, Laura, Nakamura, Brooke N., Hoang, Yvonne D., Banuelos, Jesus, Flores, Victoria N., Chan, Jefferson Y., Luderer, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690751/
https://ncbi.nlm.nih.gov/pubmed/26247513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.07.080
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