Effects of deletion of the transcription factor Nrf2 and benzo[a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice

Polycyclic aromatic hydrocarbons, like benzo[a]pyrene (BaP), are ubiquitous environmental pollutants and potent ovarian toxicants. The transcription factor NRF2 is an important regulator of the cellular response to electrophilic toxicants like BaP and to oxidative stress. NRF2 regulates transcriptio...

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Détails bibliographiques
Publié dans:Reprod Toxicol
Auteurs principaux: Lim, Jinhwan, Ortiz, Laura, Nakamura, Brooke N., Hoang, Yvonne D., Banuelos, Jesus, Flores, Victoria N., Chan, Jefferson Y., Luderer, Ulrike
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690751/
https://ncbi.nlm.nih.gov/pubmed/26247513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.07.080
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