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Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis

Polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (BaP) are ubiquitous environmental pollutants found in tobacco smoke, air pollution and grilled foods. Prenatal exposure to BaP causes premature reproductive senescence in mice, and other PAHs are transplacental ovarian carcinogens. Glut...

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Detalhes bibliográficos
Main Authors: Lim, Jinhwan, Lawson, Gregory W., Nakamura, Brooke N., Ortiz, Laura, Hur, Jin A., Kavanagh, Terrance J., Luderer, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548973/
https://ncbi.nlm.nih.gov/pubmed/23135907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3636
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