In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice

BACKGROUND: Mosaicism, the presence of genetically distinct cell populations within an organism, has emerged as an important contributor to disease. Mutational events occurring during embryonic development can cause mosaicism in any tissue, but the influence of environmental factors on levels of mos...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Environ Health Perspect
Prif Awduron: Meier, Matthew J., O’Brien, Jason M., Beal, Marc A., Allan, Beverly, Yauk, Carole L., Marchetti, Francesco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Institute of Environmental Health Sciences 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226697/
https://ncbi.nlm.nih.gov/pubmed/27448386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP211
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