Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers

Apoptosis is deregulated in most, if not all, cancers, including hematological malignancies. Smac mimetics that antagonize Inhibitor of Apoptosis (IAP) proteins have so far largely been investigated in acute myeloid leukemia (AML) cell lines; however, little is yet known on the therapeutic potential...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Lueck, Sonja C., Russ, Annika C., Botzenhardt, Ursula, Schlenk, Richard F., Zobel, Kerry, Deshayes, Kurt, Vucic, Domagoj, Döhner, Hartmut, Döhner, Konstanze, Fulda, Simone, Bullinger, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226527/
https://ncbi.nlm.nih.gov/pubmed/27385100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10390
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi