Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Aggregates of the neuronal Tau protein are found inside neurons of Alzheimer's disease patients. Development of the disease is accompanied by increased, abnormal phosphorylation of Tau. In the course of the molecular investigation of Tau functions and dysfunctions in the disease, nuclear magnet...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Danis, Clément, Despres, Clément, Bessa, Luiza M., Malki, Idir, Merzougui, Hamida, Huvent, Isabelle, Qi, Haoling, Lippens, Guy, Cantrelle, François-Xavier, Schneider, Robert, Hanoulle, Xavier, Smet-Nocca, Caroline, Landrieu, Isabelle
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2016
Предметы:
Biochemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226463/
https://ncbi.nlm.nih.gov/pubmed/28060278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55001
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