Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Aggregates of the neuronal Tau protein are found inside neurons of Alzheimer's disease patients. Development of the disease is accompanied by increased, abnormal phosphorylation of Tau. In the course of the molecular investigation of Tau functions and dysfunctions in the disease, nuclear magnet...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Danis, Clément, Despres, Clément, Bessa, Luiza M., Malki, Idir, Merzougui, Hamida, Huvent, Isabelle, Qi, Haoling, Lippens, Guy, Cantrelle, François-Xavier, Schneider, Robert, Hanoulle, Xavier, Smet-Nocca, Caroline, Landrieu, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226463/
https://ncbi.nlm.nih.gov/pubmed/28060278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55001
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