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The role of macrophages in the susceptibility of Fc gamma receptor IIb deficient mice to Cryptococcus neoformans

Dysfunctional polymorphisms of FcγRIIb, an inhibitory receptor, are associated with Systemic Lupus Erythaematosus (SLE). Cryptococcosis is an invasive fungal infection in SLE, perhaps due to the de novo immune defect. We investigated cryptococcosis in the FcγRIIb−/− mouse-lupus-model. Mortality, aft...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Surawut, Saowapha, Ondee, Thunnicha, Taratummarat, Sujittra, Palaga, Tanapat, Pisitkun, Prapaporn, Chindamporn, Ariya, Leelahavanichkul, Asada
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225418/
https://ncbi.nlm.nih.gov/pubmed/28074867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40006
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