Leaky-gut enhanced lupus progression in the Fc gamma receptor-IIb deficient and pristane-induced mouse models of lupus

The influence of gut-leakage or gut-microbiota upon lupus progression was explored in 2 lupus mouse models. Pristane, administered in 4-wk-old wild-type (WT) female mice, induced lupus characteristics at 24-wk-old similar to the lupus-onset in FcGRIIb−/− mice. Gut-microbiota alteration was induced b...

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Publicado en:Sci Rep
Autores principales: Thim-uam, Arthid, Surawut, Saowapha, Issara-Amphorn, Jiraphorn, Jaroonwitchawan, Thiranut, Hiengrach, Pratsanee, Chatthanathon, Piraya, Wilantho, Alisa, Somboonna, Naraporn, Palaga, Tanapat, Pisitkun, Prapaporn, Leelahavanichkul, Asada
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972921/
https://ncbi.nlm.nih.gov/pubmed/31964918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57275-0
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