The Synergy of Endotoxin and (1→3)-β-D-Glucan, from Gut Translocation, Worsens Sepsis Severity in a Lupus Model of Fc Gamma Receptor IIb-Deficient Mice

We investigated the influence of spontaneous gut leakage upon polymicrobial sepsis in a lupus model with Fc gamma receptor IIb-deficient (FcGRIIb−/−) mice aged 8 and 40 weeks, as representing asymptomatic and symptomatic lupus, respectively. Spontaneous gut leakage, determined by (i) the presence of...

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Bibliografske podrobnosti
izdano v:J Innate Immun
Main Authors: Issara-Amphorn, Jiraphorn, Surawut, Saowapha, Worasilchai, Navaporn, Thim-uam, Arthid, Finkelman, Malcolm, Chindamporn, Ariya, Palaga, Tanapat, Hirankarn, Nattiya, Pisitkun, Prapaporn, Leelahavanichkul, Asada
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757155/
https://ncbi.nlm.nih.gov/pubmed/29393221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000486321
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