Delta-like ligand 4 in hepatocellular carcinoma intrinsically promotes tumour growth and suppresses hepatitis B virus replication

AIM: To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS: We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tum...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Kunanopparat, Areerat, Issara-Amphorn, Jiraphorn, Leelahavanichkul, Asada, Sanpavat, Anapat, Patumraj, Suthiluk, Tangkijvanich, Pisit, Palaga, Tanapat, Hirankarn, Nattiya
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2018
Fag:
Basic Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141339/
https://ncbi.nlm.nih.gov/pubmed/30228780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v24.i34.3861
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