The role of macrophages in the susceptibility of Fc gamma receptor IIb deficient mice to Cryptococcus neoformans

Dysfunctional polymorphisms of FcγRIIb, an inhibitory receptor, are associated with Systemic Lupus Erythaematosus (SLE). Cryptococcosis is an invasive fungal infection in SLE, perhaps due to the de novo immune defect. We investigated cryptococcosis in the FcγRIIb−/− mouse-lupus-model. Mortality, aft...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Surawut, Saowapha, Ondee, Thunnicha, Taratummarat, Sujittra, Palaga, Tanapat, Pisitkun, Prapaporn, Chindamporn, Ariya, Leelahavanichkul, Asada
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225418/
https://ncbi.nlm.nih.gov/pubmed/28074867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40006
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