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Lupus-like Disease in FcγRIIB(−/−) Mice Induces Osteopenia

Osteoporotic fracture is a major cause of morbidity in patients with systemic lupus erythematosus (SLE). Mice lacking Fc gamma receptor IIb (FcγRIIB) spontaneously develop lupus-like disease or SLE at 6-month-old. The aim of this study was to investigate whether FcγRIIB deletion induces osteopenia....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Visitchanakun, Peerapat, Saiworn, Worasit, Jongwattanapisan, Prapaporn, Leelahavanichkul, Asada, Pisitkun, Prapaporn, Lotinun, Sutada
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874658/
https://ncbi.nlm.nih.gov/pubmed/31758072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53963-z
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