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Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche

BACKGROUND: Leukemic and mesenchymal stem cells interact in the leukemic microenvironment and affect each other differently. This interplay has also important implications for the hematopoietic stem cell (HSC) biology and function. This study evaluated human HSC self-renewal potential and quiescence...

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Podrobná bibliografie
Vydáno v:Exp Hematol Oncol
Hlavní autoři: Vanegas, Natalia-Del Pilar, Vernot, Jean-Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223333/
https://ncbi.nlm.nih.gov/pubmed/28078190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0062-1
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