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Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche
BACKGROUND: Leukemic and mesenchymal stem cells interact in the leukemic microenvironment and affect each other differently. This interplay has also important implications for the hematopoietic stem cell (HSC) biology and function. This study evaluated human HSC self-renewal potential and quiescence...
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| Publié dans: | Exp Hematol Oncol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223333/ https://ncbi.nlm.nih.gov/pubmed/28078190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0062-1 |
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