Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Progressive remodeling of the bone marrow microenvironment is recognized as an integral aspect of leukemogenesis. Expanding acute myeloid leukemia (AML) clones not only alter stroma composition, but also actively constrain hematopoiesis, representing a significant source of patient morbidity and mor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Abdelhamed, Sherif, Butler, John T, Doron, Ben, Halse, Amber, Nemecek, Eneida, Wilmarth, Phillip A, Marks, Daniel L, Chang, Bill H, Horton, Terzah, Kurre, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607014/
https://ncbi.nlm.nih.gov/pubmed/31267709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847546
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