Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Progressive remodeling of the bone marrow microenvironment is recognized as an integral aspect of leukemogenesis. Expanding acute myeloid leukemia (AML) clones not only alter stroma composition, but also actively constrain hematopoiesis, representing a significant source of patient morbidity and mor...

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Bibliografiska uppgifter
I publikationen:EMBO Rep
Huvudupphovsmän: Abdelhamed, Sherif, Butler, John T, Doron, Ben, Halse, Amber, Nemecek, Eneida, Wilmarth, Phillip A, Marks, Daniel L, Chang, Bill H, Horton, Terzah, Kurre, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607014/
https://ncbi.nlm.nih.gov/pubmed/31267709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847546
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