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Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche
Progressive remodeling of the bone marrow microenvironment is recognized as an integral aspect of leukemogenesis. Expanding acute myeloid leukemia (AML) clones not only alter stroma composition, but also actively constrain hematopoiesis, representing a significant source of patient morbidity and mor...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6607014/ https://ncbi.nlm.nih.gov/pubmed/31267709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847546 |
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