Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Progressive remodeling of the bone marrow microenvironment is recognized as an integral aspect of leukemogenesis. Expanding acute myeloid leukemia (AML) clones not only alter stroma composition, but also actively constrain hematopoiesis, representing a significant source of patient morbidity and mor...

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Foilsithe in:EMBO Rep
Main Authors: Abdelhamed, Sherif, Butler, John T, Doron, Ben, Halse, Amber, Nemecek, Eneida, Wilmarth, Phillip A, Marks, Daniel L, Chang, Bill H, Horton, Terzah, Kurre, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607014/
https://ncbi.nlm.nih.gov/pubmed/31267709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847546
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