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The Bone Marrow Microenvironment as Niche Retreats for Hematopoietic and Leukemic Stem Cells

Leukemia poses a serious challenge to current therapeutic strategies. This has been attributed to leukemia stem cells (LSCs), which occupy endosteal and sinusoidal niches in the bone marrow similar to those of hematopoietic stem cells (HSCs). The signals from these niches provide a viable setting fo...

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Detalhes bibliográficos
Main Authors: Nwajei, Felix, Konopleva, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556414/
https://ncbi.nlm.nih.gov/pubmed/23365579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/953982
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