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The Bone Marrow Microenvironment as Niche Retreats for Hematopoietic and Leukemic Stem Cells

Leukemia poses a serious challenge to current therapeutic strategies. This has been attributed to leukemia stem cells (LSCs), which occupy endosteal and sinusoidal niches in the bone marrow similar to those of hematopoietic stem cells (HSCs). The signals from these niches provide a viable setting fo...

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Autors principals: Nwajei, Felix, Konopleva, Marina
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556414/
https://ncbi.nlm.nih.gov/pubmed/23365579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/953982
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