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Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Progressive remodeling of the bone marrow microenvironment is recognized as an integral aspect of leukemogenesis. Expanding acute myeloid leukemia (AML) clones not only alter stroma composition, but also actively constrain hematopoiesis, representing a significant source of patient morbidity and mor...

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Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Abdelhamed, Sherif, Butler, John T, Doron, Ben, Halse, Amber, Nemecek, Eneida, Wilmarth, Phillip A, Marks, Daniel L, Chang, Bill H, Horton, Terzah, Kurre, Peter
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607014/
https://ncbi.nlm.nih.gov/pubmed/31267709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847546
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