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Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche
BACKGROUND: Leukemic and mesenchymal stem cells interact in the leukemic microenvironment and affect each other differently. This interplay has also important implications for the hematopoietic stem cell (HSC) biology and function. This study evaluated human HSC self-renewal potential and quiescence...
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| Udgivet i: | Exp Hematol Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223333/ https://ncbi.nlm.nih.gov/pubmed/28078190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0062-1 |
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