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Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche

BACKGROUND: Leukemic and mesenchymal stem cells interact in the leukemic microenvironment and affect each other differently. This interplay has also important implications for the hematopoietic stem cell (HSC) biology and function. This study evaluated human HSC self-renewal potential and quiescence...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Exp Hematol Oncol
Päätekijät: Vanegas, Natalia-Del Pilar, Vernot, Jean-Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223333/
https://ncbi.nlm.nih.gov/pubmed/28078190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0062-1
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