New insights into the GINS complex explain the controversy between existing structural models

GINS is a key component of eukaryotic replicative forks and is composed of four subunits (Sld5, Psf1, Psf2, Psf3). To explain the discrepancy between structural data from crystallography and electron microscopy (EM), we show that GINS is a compact tetramer in solution as observed in crystal structur...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Carroni, Marta, De March, Matteo, Medagli, Barbara, Krastanova, Ivet, Taylor, Ian A., Amenitsch, Heinz, Araki, Hiroyuchi, Pisani, Francesca M., Patwardhan, Ardan, Onesti, Silvia
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223209/
https://ncbi.nlm.nih.gov/pubmed/28071757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40188
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