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New insights into the GINS complex explain the controversy between existing structural models

GINS is a key component of eukaryotic replicative forks and is composed of four subunits (Sld5, Psf1, Psf2, Psf3). To explain the discrepancy between structural data from crystallography and electron microscopy (EM), we show that GINS is a compact tetramer in solution as observed in crystal structur...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Carroni, Marta, De March, Matteo, Medagli, Barbara, Krastanova, Ivet, Taylor, Ian A., Amenitsch, Heinz, Araki, Hiroyuchi, Pisani, Francesca M., Patwardhan, Ardan, Onesti, Silvia
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223209/
https://ncbi.nlm.nih.gov/pubmed/28071757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40188
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