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Cryo-electron microscopy reveals a novel DNA-binding site on the MCM helicase
The eukaryotic MCM2–7 complex is recruited at origins of replication during the G1 phase and acts as the main helicase at the replication fork during the S phase of the cell cycle. To characterize the interplay between the MCM helicase and DNA prior to the melting of the double helix, we determined...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519097/ https://ncbi.nlm.nih.gov/pubmed/18650940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.135 |
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