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Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein
Minichromosome maintenance (MCM) helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during replication. In archaea, the catalytic activity resides within the C-terminal region of the MCM protein. In Methanothermobacter thermautotrophicus the N...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275104/ https://ncbi.nlm.nih.gov/pubmed/18184696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1160 |
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