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Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein

Minichromosome maintenance (MCM) helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during replication. In archaea, the catalytic activity resides within the C-terminal region of the MCM protein. In Methanothermobacter thermautotrophicus the N...

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Detalhes bibliográficos
Main Authors: Sakakibara, Nozomi, Kasiviswanathan, Rajesh, Melamud, Eugene, Han, Mimi, Schwarz, Frederick P., Kelman, Zvi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275104/
https://ncbi.nlm.nih.gov/pubmed/18184696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1160
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