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Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein

Minichromosome maintenance (MCM) helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during replication. In archaea, the catalytic activity resides within the C-terminal region of the MCM protein. In Methanothermobacter thermautotrophicus the N...

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Bibliografiska uppgifter
Huvudupphovsmän: Sakakibara, Nozomi, Kasiviswanathan, Rajesh, Melamud, Eugene, Han, Mimi, Schwarz, Frederick P., Kelman, Zvi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275104/
https://ncbi.nlm.nih.gov/pubmed/18184696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1160
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