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Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases
Cdc45 is an essential protein conserved in all eukaryotes and is involved both in the initiation of DNA replication and the progression of the replication fork. With GINS, Cdc45 is an essential cofactor of the Mcm2–7 replicative helicase complex. Despite its importance, no detailed information is av...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281742/ https://ncbi.nlm.nih.gov/pubmed/22147708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285395 |
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