A carregar...

Structure of human Cdc45 and implications for CMG helicase function

Cell division cycle protein 45 (Cdc45) is required for DNA synthesis during genome duplication, as a component of the Cdc45-MCM-GINS (CMG) helicase. Despite its essential biological function, its biochemical role in DNA replication has remained elusive. Here we report the 2.1-Å crystal structure of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Simon, Aline C., Sannino, Vincenzo, Costanzo, Vincenzo, Pellegrini, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873980/
https://ncbi.nlm.nih.gov/pubmed/27189187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11638
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!