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Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin

The chromosomal DNA replication in eukaryotic cells begins at replication initation sites, which are marked by the assembly of the pre-replication complexes in early G1. At the G1/S transition, recruitment of additional replication initiation proteins enables origin DNA unwinding and loading of DNA...

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Publicat a:Exp Cell Res
Autors principals: Gerhardt, Jeannine, Guler, Gulfem D., Fanning, Ellen
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439256/
https://ncbi.nlm.nih.gov/pubmed/25933514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.04.014
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