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Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin

The chromosomal DNA replication in eukaryotic cells begins at replication initation sites, which are marked by the assembly of the pre-replication complexes in early G1. At the G1/S transition, recruitment of additional replication initiation proteins enables origin DNA unwinding and loading of DNA...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Cell Res
Hauptverfasser: Gerhardt, Jeannine, Guler, Gulfem D., Fanning, Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439256/
https://ncbi.nlm.nih.gov/pubmed/25933514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.04.014
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