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Initiation-specific alleles of the Cdc45 helicase-activating protein

The committed step in DNA replication initiation is the activation of the Mcm2-7 replicative DNA helicase. Two activators, Cdc45 and GINS, associate with Mcm2-7 at origins of replication to form the CMG complex, which is the active eukaryotic replicative helicase. These activators function during bo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rios-Morales, Ramon Y., Chan, Sze Ham, Bell, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435160/
https://ncbi.nlm.nih.gov/pubmed/30913274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214426
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