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Initiation-specific alleles of the Cdc45 helicase-activating protein
The committed step in DNA replication initiation is the activation of the Mcm2-7 replicative DNA helicase. Two activators, Cdc45 and GINS, associate with Mcm2-7 at origins of replication to form the CMG complex, which is the active eukaryotic replicative helicase. These activators function during bo...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6435160/ https://ncbi.nlm.nih.gov/pubmed/30913274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214426 |
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