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p53 Deficiency Rescues Neuronal Apoptosis but Not Differentiation in DNA Polymerase β-Deficient Mice
In mammalian cells, DNA polymerase β (Polβ) functions in base excision repair. We have previously shown that Polβ-deficient mice exhibit extensive neuronal cell death (apoptosis) in the developing nervous system and that the mice die immediately after birth. Here, we studied potential roles in the p...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC522222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15485914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.21.9470-9477.2004 |
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